{"id":11233,"date":"2021-09-03T08:11:00","date_gmt":"2021-09-03T08:11:00","guid":{"rendered":"https:\/\/stop-allergy-meds.com\/blog\/?p=11233"},"modified":"2021-10-13T08:12:15","modified_gmt":"2021-10-13T08:12:15","slug":"antibiotic-allergy-which-causes-it-most-often","status":"publish","type":"post","link":"https:\/\/stop-allergy-meds.com\/blog\/antibiotic-allergy-which-causes-it-most-often\/","title":{"rendered":"Antibiotic allergy: which causes it most often?"},"content":{"rendered":"\n<p><strong>Antibiotic allergy is one of the manifestations of drug allergy.&nbsp;It is characterized by the particular severity of the reactions that arise.&nbsp;Allergies are the most common cause of life-threatening immune-mediated drug responses.&nbsp;Including &#8211; anaphylaxis, as well as &#8211; severe skin side reactions and specific reactions from individual organs.<\/strong><\/p>\n\n\n\n<p>According to various sources, an allergy to antibiotics is observed in about 10-15% of the world&#8217;s inhabitants.&nbsp;However, most of the negative effects are caused by&nbsp;<strong>penicillin&nbsp;<\/strong>.&nbsp;The first reactions to it began to be recorded almost immediately after the widespread use of this antibiotic in the 1940s.&nbsp;Today, it is believed (although this figure is questioned due to imperfect diagnostics) that&nbsp;<strong>about 10% of people with allergies react to penicillin&nbsp;<\/strong>.&nbsp;In developed countries, from 5% to 15% of such patients have a mark on the medical card about penicillin allergy.&nbsp;<strong><\/strong>&nbsp;<strong><\/strong><\/p>\n\n\n\n<p><strong>Penicillin antibiotics include:<\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>amoxicillin<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>ampicillin<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>dikloksatsilin<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>naftsilin<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>oxacillin<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>Penicillin g<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>Penicillin v<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>piperacillin<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>tikartsilin<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p>Antibiotics from the&nbsp;<strong>sulfonamide \/ cephalosporin&nbsp;<\/strong>group are also common triggers of an allergic reaction&nbsp;<strong>.<\/strong>&nbsp;<strong><\/strong><\/p>\n\n\n\n<p><strong>They include:<\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>cefaclor<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>cefadroxil<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>cefazolin<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>cefdinir<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>Cefepime (maksipin)<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>tsefotetan<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>cefprozil<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>cefuroxime<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>Cephalexin (kefleks)<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p>The danger of an antibiotic allergy is that no one knows when a reaction might occur.&nbsp;For example, the immune system can become sensitive to an antibacterial drug the first time it is taken.&nbsp;Therefore, the next time an allergic reaction may occur.<\/p>\n\n\n\n<p><strong>CAUSES OF ANTIBIOTIC ALLERGY<\/strong><\/p>\n\n\n\n<p><strong>Antibiotic allergies are unpredictable.&nbsp;But there are a number of other factors that increase the risks of its occurrence.<\/strong><\/p>\n\n\n\n<p>These include:<\/p>\n\n\n\n<p><strong>\u00b7 The&nbsp;<\/strong><strong>presence of other allergies, for example, to cats, food, hay fever;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>A&nbsp;<\/strong><strong>family history of antibiotic allergy<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>Frequent use of antibiotics;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>Long-term disease that makes the immune system more sensitive;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>Increased exposure to high doses of penicillin via,<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>\u00b7&nbsp;<\/strong><strong>Repeated or prolonged use.<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong>&nbsp;<\/strong><strong><\/strong><\/p>\n\n\n\n<p><strong>Some illnesses, such as HIV or the presence of the Epstein-Barr virus, are also associated with an allergic response to medications.<\/strong><\/p>\n\n\n\n<p>In particular, a high prevalence (23-35%) of registered antibiotic allergy is observed in cancer patients.&nbsp;Patients with HIV \/ AIDS also have a high frequency of reports of drug allergies (up to one in four).&nbsp;In this group of patients, the frequency of skin reactions is 10-100 times higher than usual.&nbsp;In this case, sulfonamides most often cause reactions.&nbsp;More than 10% of HIV patients have a history of intolerance or allergy to these antibiotics.<\/p>\n\n\n\n<p>Sensitivity to other types of antibiotics also increases the risk of a reaction.&nbsp;<strong>So, in patients allergic to penicillin, the risk of adverse reactions to any medications increases threefold.&nbsp;<\/strong>It has also been reported that cephalosporin allergy develops in about 2% of patients who have had immediate reactions and a positive skin test for penicillins in the past.&nbsp;<strong><\/strong>&nbsp;<\/p>\n\n\n\n<p><strong>SYMPTOMS OF ANTIBIOTIC ALLERGY<\/strong><\/p>\n\n\n\n<p><strong><em>Allergies after the use of antibiotics&nbsp;<\/em><\/strong>can appear immediately, as well as &#8211; in a few days, or even weeks after stopping them.&nbsp;<\/p>\n\n\n\n<p>Symptoms of an allergic reaction can also vary.&nbsp;Manifestations can affect the skin, respiratory system, digestive system, cardiovascular system, etc.<\/p>\n\n\n\n<p><strong>The main symptoms of antibiotic allergy are:<\/strong><\/p>\n\n\n\n<ul><li>skin rash<\/li><li>hives<\/li><li>fever<\/li><li>edema<\/li><li>dyspnea<\/li><li>wheezing<\/li><li>runny nose<\/li><li>conjunctivitis<\/li><li>anaphylaxis<\/li><\/ul>\n\n\n\n<p><strong><em>Allergy to antibiotics.&nbsp;<\/em><\/strong><strong>Rash.<\/strong><strong><em>&nbsp;<\/em><\/strong><strong><\/strong><\/p>\n\n\n\n<p>Skin rashes are common and one of the main signs of an antibiotic allergy.<\/p>\n\n\n\n<p>Moderate skin symptoms include itching, redness, flaking, and swelling.&nbsp;Even red patches may appear on the skin, covered with small bumps.&nbsp;Or&nbsp;<strong>hives&nbsp;<\/strong>develop&nbsp;.&nbsp;<strong><\/strong><\/p>\n\n\n\n<p><strong>The main signs of hives are white or red bumps on the skin that appear after one or two doses of the medication.&nbsp;<\/strong>In this case, you need to stop taking the drug and immediately consult a doctor.&nbsp;After all, the reaction can intensify.&nbsp;<\/p>\n\n\n\n<p>Very often, urticaria appears after the use of penicillin antibiotics.<\/p>\n\n\n\n<p>However, even a rash caused by penicillins is not always allergic.&nbsp;It can also be a side effect of their action.&nbsp;For example, the most common T cell mediated response to antibiotics is maculopapular rash.&nbsp;This reaction is observed with the use of aminopenicillin.&nbsp;And forms the so-called&nbsp;<strong>&#8220;amoxicillin rash&#8221;&nbsp;<\/strong>.&nbsp;It is, as the name suggests, often caused by amoxicillin, which belongs to the penicillin series.&nbsp;<strong><\/strong><\/p>\n\n\n\n<p><strong>This rash resembles flat, red patches.&nbsp;And it is she who often appears late &#8211; between 3 and 10 days after the start of taking amoxicillin.&nbsp;<\/strong>However, the reaction can manifest itself at other times.<strong>&nbsp;<\/strong><\/p>\n\n\n\n<p>Other specific skin adverse reactions from antibiotics include rash caused by tetracyclines, sulfonamides, \u03b2-lactam, vancomycin, and fluconazole.&nbsp;For example, vancomycin is the most common cause of antibiotic linear bullous, IgA-dependent disease, a blistering cutaneous adverse reaction that can also mimic Stevens-Johnson syndrome and toxic epidermal necrolysis.<\/p>\n\n\n\n<p>Hives or rashes can also appear with other antibiotics.<\/p>\n\n\n\n<p>For example, an&nbsp;<em>allergy to&nbsp;<\/em><em>ceftriaxone&nbsp;<\/em>, which is a popular broad-spectrum antibiotic, is characterized by symptoms such as:&nbsp;<em><\/em><em>&nbsp;<\/em><em><\/em><\/p>\n\n\n\n<ul><li>hives,<\/li><li>hindered<\/li><li>breath,<\/li><li>swelling of the face or throat.<\/li><\/ul>\n\n\n\n<p>In severe cases, the skin may blister, peel off, and swell.&nbsp;Severe itching may be felt, as well as sore throat and fever.<\/p>\n\n\n\n<p>Antibiotics can sometimes cause anaphylaxis.&nbsp;<strong>Anaphylaxis is a sudden, life-threatening reaction that requires immediate treatment (epinephrine).&nbsp;<\/strong>Anaphylactic shock with an allergy to antibiotics can develop both independently and under certain conditions, for example, after playing sports.&nbsp;<strong><\/strong>&nbsp;<\/p>\n\n\n\n<p><strong>Symptoms of anaphylaxis include:<\/strong><\/p>\n\n\n\n<ul><li>a feeling of tightness in the throat<\/li><li>breathing problems<\/li><li>tingling<\/li><li>swelling<\/li><li>dizziness,<\/li><li>cardiopalmus,<\/li><li>wheezing.<\/li><\/ul>\n\n\n\n<p>If you suspect anaphylaxis, you need to immediately call an ambulance, or, if available, self-administer adrenaline.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Antibiotic allergy is one of the manifestations of drug allergy.&nbsp;It is characterized by the particular severity of the reactions that arise.&nbsp;Allergies are the most common cause of life-threatening immune-mediated drug responses.&nbsp;Including &#8211; anaphylaxis, as well as &#8211; severe skin side reactions and specific reactions from individual organs. According to various<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/stop-allergy-meds.com\/blog\/wp-json\/wp\/v2\/posts\/11233"}],"collection":[{"href":"https:\/\/stop-allergy-meds.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stop-allergy-meds.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stop-allergy-meds.com\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/stop-allergy-meds.com\/blog\/wp-json\/wp\/v2\/comments?post=11233"}],"version-history":[{"count":1,"href":"https:\/\/stop-allergy-meds.com\/blog\/wp-json\/wp\/v2\/posts\/11233\/revisions"}],"predecessor-version":[{"id":11234,"href":"https:\/\/stop-allergy-meds.com\/blog\/wp-json\/wp\/v2\/posts\/11233\/revisions\/11234"}],"wp:attachment":[{"href":"https:\/\/stop-allergy-meds.com\/blog\/wp-json\/wp\/v2\/media?parent=11233"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stop-allergy-meds.com\/blog\/wp-json\/wp\/v2\/categories?post=11233"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stop-allergy-meds.com\/blog\/wp-json\/wp\/v2\/tags?post=11233"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}